What is Papilloguard®?

Papilloguard® is a vaccine given to individuals 9 through 26 years of age to help protect against diseases caused by some types of Human Papilloma virus (HPV).

What is in Papilloguard®?

Papilloguard® contains:

  • Proteins of HPV Types 16,18
  • The 3-O-desacyl-4’-monophosphoryl lipid A (MPL),
  • Aluminum (as hydroxide salt)

What diseases can Papilloguard® help to prevent?

In girls from the age 9, helps to prevent:

  • Cervical cancer
  • Vulvar and vaginal cancers
  • Anal cancer
  • Precancerous cervical, vulvar, vaginal and anal lesions

What do I need to tell my doctor before I take this drug?

  • If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have an infection or an illness with a fever.
  • If you are pregnant or may be pregnant. Do not use this drug if you are pregnant.
  • This is not a list of all drugs or health problems that interact with this drug.
  • Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.




15 through 45 years

3 doses

0, 1, 6 months

How is Papilloguard®given?

*If the second shot is given earlier than 5 months after the first shot, you will need to get a third shot at least 4 months after the second shot was given.
**The need to use a 3-dose schedule instead of a 2-dose schedule will be determined by your health care professional. Make sure that you or your child gets all doses recommended by your health care professional so that you or your child gets the best protection. If the person getting Papilloguard® misses a dose, tell the health care professional and they will decide when to give the missed dose. It is important that you follow the instructions of your health care professional regarding return visits for the follow-up doses.
Fainting can happen after getting an HPV vaccine. Sometimes people who faint can fall and hurt themselves. For this reason, the health care professional may ask the person getting Papilloguard® to sit or lie down for 15 minutes after getting the vaccine. Some people who faint might shake or become stiff.

Can I get Papilloguard®with other vaccines?

You can get Papilloguard®vaccine and other vaccines at the same visit

What are some things I need to know or do while I take this vaccine?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • This drug may not protect all people who use it. Talk with the doctor.
  • If you have HPV, talk with your doctor.
  • Be sure to have regular gynecology check-ups. Your doctor will tell you how often to have these.
  • Use birth control to prevent pregnancy for 2 months after getting this drug.
  • If you get pregnant within 2 months after getting this drug, call your doctor right away.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • Papilloguard®does not treat HPV infection.
  • Papilloguard®does not protect the person from getting HPV types that he/she may already have.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling tired or weak.
  • Headache.
  • Muscle or joint pain.
  • Stomachache.
  • Diarrhea.
  • Abdominal pain.
  • Fever.
  • Pain at injection site.
  • Redness at injection site.

How is this vaccine best taken?

  • Use this vaccine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
  • It is given as a shot into deltoid muscle.

What do I do if I missed a dose?

Call your doctor to find out.

How do I store and/or throw out this drug?

If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.

General drug facts:

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.